TUBE1

TUBE1
Identifiers
Aliases	TUBE1, TUBE, dJ142L7.2, tubulin epsilon 1
External IDs	OMIM: 607345; MGI: 1919174; HomoloGene: 17762; GeneCards: TUBE1; OMA:TUBE1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q21 Start 112,070,663 bp[1] End 112,087,529 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 B1 Start 39,133,976 bp[2] End 39,152,542 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum oocyte secondary oocyte pancreatic epithelial cell Achilles tendon body of uterus right lobe of liver cardiac muscle tissue of right atrium right auricle C1 segment Top expressed in thymus secondary oocyte medullary collecting duct hand neural layer of retina primary oocyte primitive streak zygote renal corpuscle genital tubercle More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding GTP binding structural constituent of cytoskeleton GTPase activity Cellular component cytoplasm microtubule pericentriolar material cytoskeleton microtubule organizing center Biological process centrosome cycle microtubule-based process microtubule cytoskeleton organization mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51175 71924 Ensembl ENSG00000074935 ENSMUSG00000019845 UniProt Q9UJT0 Q9D6T1 RefSeq (mRNA) NM_016262 NM_028006 RefSeq (protein) NP_057346 NP_082282 Location (UCSC) Chr 6: 112.07 – 112.09 Mb Chr 10: 39.13 – 39.15 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tubulin, epsilon 1 is a protein in humans that is encoded by the TUBE1 gene.^[5] This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication

References

Further reading