Sulbentine

Chemical compound

Identifiers

CAS Number

PubChem CID

ChemSpider

UNII

KEGG

CompTox Dashboard (EPA)

ECHA InfoCard100.005.907

Chemical and physical dataFormulaC₁₇H₁₈N₂S₂Molar mass314.46 g·mol⁻¹3D model (JSmol)

InChI

InChI=1S/C17H18N2S2/c20-17-19(12-16-9-5-2-6-10-16)13-18(14-21-17)11-15-7-3-1-4-8-15/h1-10H,11-14H2^N
Key:QFVAWNPSRQWSDU-UHFFFAOYSA-N^N

^NY (what is this?) (verify)

Sulbentine (or dibenzthione) is an antifungal.^[1]

References

^ Hänel H, Raether W, Dittmar W (1988). "Evaluation of fungicidal action in vitro and in a skin model considering the influence of penetration kinetics of various standard antimycotics". Annals of the New York Academy of Sciences. 544 (1): 329–37. Bibcode:1988NYASA.544..329H. doi:10.1111/j.1749-6632.1988.tb40417.x. PMID 3214073. S2CID 13183316.

Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles (lanosterol 14α-
demethylase inhibitors)

Imidazoles	Topical: bifonazole^‡ butoconazole chlormidazole^‡ climbazole clotrimazole^# croconazole^‡ eberconazole econazole fenticonazole^‡ flutrimazole isoconazole ketoconazole luliconazole miconazole^# neticonazole^‡ omoconazole^‡ oxiconazole sertaconazole sulconazole tioconazole Systemic: ketoconazole
Triazoles	Topical: efinaconazole fluconazole^# terconazole Systemic: fluconazole^# fosfluconazole fosravuconazole hexaconazole^‡ isavuconazole itraconazole^# oteseconazole posaconazole voriconazole^# Unknown: albaconazole^‡ ravuconazole^†
Thiazoles	Topical: abafungin^‡

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine
Benzylamines	Topical: butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	Systemic: flucytosine^#
Mitotic inhibitors	Systemic: griseofulvin^#
Aminoacyl tRNA synthetase inhibitors	Topical: tavaborole