Ccl12 |
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Identifiers |
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Aliases | chemokine (C-C motif) ligand 12MCP-5Scya12 |
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External IDs | HomoloGene: 2245 GeneCards: [1] |
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Gene location (Human) |
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| Chr. | Chromosome 11 (human) |
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| Band | 11 C|11 49.9 cM | Start | 81,992,671 bp |
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End | 81,994,226 bp |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - cervix
- thymus
- subcutaneous adipose tissue
- aortic valve
- dermis
- white adipose tissue
- lip
- zone of skin
- optic nerve
- mammary gland
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| | More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - cytokine activity
- CCR2 chemokine receptor binding
- chemokine activity
- protein kinase activity
- phospholipase activator activity
- CCR chemokine receptor binding
| Cellular component | - extracellular region
- intracellular anatomical structure
- extracellular space
| Biological process | - negative regulation of neuron apoptotic process
- G protein-coupled receptor signaling pathway
- protein kinase B signaling
- monocyte chemotaxis
- astrocyte cell migration
- cytokine-mediated signaling pathway
- chemokine-mediated signaling pathway
- negative regulation of glial cell apoptotic process
- cellular response to tumor necrosis factor
- negative regulation of natural killer cell chemotaxis
- cellular response to organic cyclic compound
- neutrophil chemotaxis
- MAPK cascade
- chemotaxis
- positive regulation of GTPase activity
- positive regulation of calcium ion import
- macrophage chemotaxis
- cytoskeleton organization
- angiogenesis
- immune response
- cellular response to interleukin-1
- positive regulation of ERK1 and ERK2 cascade
- regulation of cell shape
- cellular response to interferon-gamma
- lymphocyte chemotaxis
- inflammatory response
- lipopolysaccharide-mediated signaling pathway
- regulation of signaling receptor activity
- positive regulation of leukocyte migration
- negative regulation of leukocyte proliferation
- negative regulation of vascular endothelial cell proliferation
- negative regulation of G1/S transition of mitotic cell cycle
- positive regulation of endothelial cell apoptotic process
- calcium ion transport
- cellular calcium ion homeostasis
- exocytosis
- cell-cell signaling
- eosinophil chemotaxis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 11: 81.99 – 81.99 Mb | n/a |
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PubMed search | [1] | n/a |
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Wikidata |
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