CASZ1

Protein-coding gene in the species Homo sapiens
CASZ1
Identifiers
AliasesCASZ1, CAS11, CST, SRG, ZNF693, dJ734G22.1, castor zinc finger 1
External IDsOMIM: 609895; MGI: 1196251; HomoloGene: 9824; GeneCards: CASZ1; OMA:CASZ1 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for CASZ1
Genomic location for CASZ1
Band1p36.22Start10,636,604 bp[1]
End10,796,650 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for CASZ1
Genomic location for CASZ1
Band4 E2|4 78.87 cMStart148,888,886 bp[2]
End149,039,346 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of leg

  • skin of abdomen

  • muscle of thigh

  • pancreatic ductal cell

  • buccal mucosa cell

  • gastrocnemius muscle

  • bronchial epithelial cell

  • skin of arm

  • muscle layer of sigmoid colon

  • body of stomach
Top expressed in
  • lip

  • neural layer of retina

  • muscle of thigh

  • gastrula

  • lumbar spinal ganglion

  • esophagus

  • interventricular septum

  • internal carotid artery

  • hair follicle

  • prostate
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • metal ion binding
  • DNA binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular membrane-bounded organelle
  • nucleoplasm
  • cytosol
  • nucleus
Biological process
  • multicellular organism development
  • regulation of transcription, DNA-templated
  • regulation of neuron differentiation
  • positive regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

54897

69743

Ensembl

ENSG00000130940

ENSMUSG00000028977

UniProt

Q86V15

Q9CWL2

RefSeq (mRNA)

NM_001039183
NM_001079843
NM_017766

NM_001159344
NM_027195

RefSeq (protein)

NP_001073312
NP_060236

NP_001152816
NP_081471

Location (UCSC)Chr 1: 10.64 – 10.8 MbChr 4: 148.89 – 149.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Putative survival-related protein is a protein that in humans is encoded by the CASZ1 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130940 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028977 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Liu Z, Yang X, Tan F, Cullion K, Thiele CJ (May 2006). "Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation". Biochem Biophys Res Commun. 344 (3): 834–44. doi:10.1016/j.bbrc.2006.03.207. PMID 16631614.
  6. ^ "Entrez Gene: CASZ1 castor zinc finger 1".

External links

Further reading

  • Fernandez F, Curtain RP, Colson NJ, et al. (2007). "Association analysis of chromosome 1 migraine candidate genes". BMC Med. Genet. 8: 57. doi:10.1186/1471-2350-8-57. PMC 2034370. PMID 17727731.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Yuan ZR, Wang R, Solomon J, et al. (2006). "Identification and characterization of survival-related gene, a novel cell survival gene controlling apoptosis and tumorigenesis". Cancer Res. 65 (23): 10716–24. doi:10.1158/0008-5472.CAN-05-2176. PMID 16322216.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


  • v
  • t
  • e